18 Mange Shampoos to Tame Itching and Flakes

Discover the best mange shampoo to soothe, heal, and renew your scalp with our quick guide to top-rated, effective solutions for healthy hair.
BrandMy RatingPrice
Veterinary Formula
Affordable Winner
9.0/10
Veterinary Formula
Best for Sensitive Skin
9.2/10
Renuplex
Best Natural Remedy
8.8/10
Happy Jack
Best Fast-Acting Relief
8.0/10
Healthyanimals4ever
8.0/10

Best Mange Shampoo

Struggling with dandruff or an itchy scalp? Discovering the perfect mange shampoo doesn't have to be a voyage through endless bottles. Here, we’ve curated the top-rated solutions designed to tame those pesky flakes and restore scalp serenity in just a few simple steps.

Affordable Winner: Veterinary Formula

Veterinary Formula Clinical Care Antiparasitic & Antiseborrheic Medicated Dog Shampoo, 16 oz – Paraben, Dye, Soap Free – Hydrating and Antifungal Shampoo for Dogs, White
Highlights
Promotes healthy skin
Fast-acting, effective
Vet-recommended formulation

As our "Affordable Winner," this medicated shampoo strikes a fantastic balance between quality and price.

It effectively helps shed dry skin and soothe irritation, thanks to ingredients like oatmeal, allantoin, and vitamin E.

Although it has a strong medicated scent, its fast-acting formula delivers results in just a few baths, making it perfect for quick relief.

Loved by many pet owners and vet-recommended, it’s a reliable choice for those seeking budget-friendly, medicated care.

Keep in mind, it's not suitable for cats, but for dogs, it's a go-to for healthy, happy skin.

Be sure to also check out the best wig shampoo for more options! Also, here is the price history so you know exactly when to buy!

Price history for Veterinary Formula on Amazon

Best for Sensitive Skin: Veterinary Formula

Veterinary Formula Clinical Care Antiseptic and Antifungal Medicated Shampoo for Dogs & Cats, 16 Fl Oz – Helps Alleviate Scaly, Greasy, red Skin – Paraben, Dye, Soap-Free (1 Pack)
Highlights
Effective skin relief
Gentle and soothing
Affordable veterinary alternative

As the best for sensitive skin, it’s formulated with gentle, soap-free, paraben-free ingredients like oatmeal and allantoin, making it a soothing choice for pets with irritation or allergies.

It works fast — a 5-10 minute soak helps calm red, greasy, or stinky skin, providing immediate relief.

Plus, being vet-recommended and pH balanced, it promotes healthy skin and coat without harsh chemicals.

While it does require regular use and has a slight longer bath time, the soothing results make it well worth the effort, especially for those dealing with sensitive skin issues.

Be sure to also check out the best mielle shampoo for more options! Also, here is the price history so you know exactly when to buy!

Price history for Veterinary Formula on Amazon

Best Natural Remedy: RenuPlex

Medicated Dog Mange Shampoo. Extra Strength Mange Shampoo for Dogs Eliminates Mange, Scabies & Severe Skin Problems. All Natural Dog Shampoo. Unconditional Guarantee. Made in USA…
Highlights
Natural healing ingredients
Effective against mange
Soothes skin irritation

RenuPlex Extra Strength is our top pick for the best natural remedy for dog mange.

This shampoo boasts a powerful blend of essential oils, colloidal oatmeal, aloe vera, and jojoba oil, making it gentle yet effective for irritated skin.

While it might seem a bit pricey and requires some patience with multiple washes, its all-natural ingredients and proven effectiveness truly make it stand out.

We love that it soothes and helps repair damaged skin safely and naturally, earning it a solid reputation among pet owners.

Be sure to also check out the best chi shampoo for more options! Also, here is the price history so you know exactly when to buy!

Price history for RenuPlex on Amazon

Best Fast-Acting Relief: HAPPY JACK

HAPPY JACK Mange Medicine & Treatment for Dogs & Horses - Brings Soothing Itch Relief to Severe Mange, Fungi, Allergies, Eczema & Most Dog Skin Irritation (8 oz)
Highlights
Fast-acting relief
Effective for mange
Soothes irritated skin

Happy Jack's longstanding reputation as the original mange remedy since 1946 really shows.

Its fast-acting formula begins to soothe severe irritation within just a few days, making it a top pick for stubborn cases.

The treatment is federally approved and trusted, offering peace of mind that you're using a safe, effective solution.

While the strong chemical smell and lingering house odor might be a downside, the quick relief and proven track record make it a go-to for pet owners desperate for swift results.

Be sure to also check out the best violet shampoo for more options! Also, here is the price history so you know exactly when to buy!

Price history for HAPPY JACK on Amazon

HealthyAnimals4Ever

HealthyAnimals4Ever Mange Relief for Dogs - Treatment for Itchiness, Scabs, & Hair Loss Caused by Mites - All-Natural, Homeopathic, Non-GMO, Organic - Gluten, Preservative & Chemical Free - 300 ct
Highlights
Effective skin relief
Natural ingredients
Made in USA

HealthyAnimals4Ever's homeopathic pellets are a gentle yet effective solution for mange relief in dogs.

Their natural blend of organic minerals tackles itchiness, inflammation, and hair loss without harsh chemicals, making it a safe choice for sensitive pups.

We appreciate that they're made in the USA with high-quality standards, giving pet owners peace of mind.

While some users note a slow response or mixed reviews on effectiveness, the natural ingredients and tailored dosing options make this a trustworthy addition to your pet's wellness routine.

Be sure to also check out the best yucca shampoo for more options! Also, here is the price history so you know exactly when to buy!

Price history for HealthyAnimals4Ever on Amazon

HAPPY JACK

HAPPY JACK Mange Medicine & Treatment for Dogs & Horses - Brings Soothing Itch Relief to Severe Mange, Fungi, Allergies, Eczema & Most Dog Skin Irritation (8 oz)
Highlights
Fast-acting relief
Effective for mange
Trusted since 1946

Happy Jack Mange Medicine is a true veteran in the pet care world, trusted since 1946 and still going strong.

Its fast-acting formula gets to work within days, effectively soothing irritated skin and targeting stubborn mange with reliable results.

While it does have a strong odor, its time-tested effectiveness makes it worth it for many pet owners.

Just a heads-up: the instructions on dilution could be clearer, and some pets might experience minor skin irritation.

Overall, it’s a dependable choice for those seeking quick relief with a trusted legacy.

Be sure to also check out the best ginger shampoo for hair loss for more options! Also, here is the price history so you know exactly when to buy!

Price history for HAPPY JACK on Amazon

Pet Honesty Chlorhexidine Dog Shampoo Mange Shampoo

Pet Honesty Chlorhexidine Cat & Dog Seasonal Itch Relief Shampoo, for Allergies, Itching, Dog Skin and Coat Supplement, Helps Shedding, Hot Spots, Deodorizing Dog Shampoo, Dog Grooming Supplies,16oz
Highlights
Effective skin treatment
Soothes irritated skin
Pleasant cucumber melon scent

PetHonesty's Chlorhexidine Shampoo is a big win for pet owners seeking a vet-recommended solution.

Its blend of Chlorhexidine and Ketoconazole works effectively to target skin issues, leaving your furry friend’s coat feeling refreshed, soothed, and beautifully shiny.

Plus, the light cucumber melon scent makes bath time a treat, not a chore.

While it may require a couple of washes to fully tame persistent itching, its calming aloe addition helps ease irritated skin.

The easy-to-use pump and high-quality ingredients in a U.

S.-made formula make it a reliable choice for maintaining your pet's skin health.

Be sure to also check out the best weave shampoo and conditioner for more options! Also, here is the price history so you know exactly when to buy!

Price history for Pet Honesty Chlorhexidine Dog Shampoo on Amazon

Pet MD

Pet MD - Benzoyl Peroxide Medicated Shampoo for Dogs and Cats - Effective for Skin Conditions, Dandruff, Itch Relief, Acne and Folliculitis - Citrus Scent - 12 oz
Highlights
Calms skin irritation
Effective dandruff reduction
Gentle, medicated formula

Pet MD's Benzoyl Medicated Shampoo offers gentle yet powerful relief for irritated skin, fighting off dandruff, fungi, and bacteria with its medicated formula.

The use of peroxide and sulfur ensures a thorough clean that leaves coats fresh and oils controlled.

While its medical scent might be a bit strong for some, its effectiveness in calming skin and reducing itchiness really shines.

Just a heads-up—it's not designed for daily use, but when used as directed, it’s a reliable ally in your pet’s skincare routine.

Be sure to also check out the best vegan shampoo bar for more options! Also, here is the price history so you know exactly when to buy!

Price history for Pet MD on Amazon

Ovante

Dog n Mite Anti-Mange Shampoo for Dogs & Puppies with Demodex Mange, Itching, Hot Spot - 6.0 oz
Highlights
Effective mange treatment
Supports healthy skin
Made in USA

Ovante’s Veterinary Formula Clinical Care shampoo is a strong contender for tackling mange and irritated skin.

Its powerful healing properties help soothe itching and support skin repair, making it a go-to for dogs recovering from demodex issues.

Plus, it’s crafted right here in the USA, ensuring quality and safety.

The thick lather and effective formula leave coats looking vibrant and healthy.

While the scent is a bit potent and the ingredient list isn’t fully transparent, its clinical effectiveness and supportive care make it worth considering for pet parents seeking real relief.

Be sure to also check out the best shampoo coconut for more options! Also, here is the price history so you know exactly when to buy!

Price history for Ovante on Amazon

Arava Dog Shampoo Mange Shampoo

Arava Natural Medicated Dog Shampoo – Anti Yeast Anti Itch Dog Shampoo - Healthy Skin & Coat - First Aid in Hot Spots Ringworm Scrapes Abrasions & Dermatologic Infections - 400ml / 13.5 fl oz
Highlights
Reduces skin irritations
Natural, active ingredients
Deep, effective cleansing

Arava Therapeutic Shampoo harnesses the power of Dead Sea minerals combined with 28 natural ingredients, making it a standout for soothing irritated skin and tackling dermatological issues.

Its deep-cleaning formula gently lifts dirt and excess oils without stripping away moisture, leaving your dog's coat shiny and fresh.

Plus, the botanical oils help reduce skin infections, promoting overall skin health.

While it comes at a premium price, many users find the effectiveness worth it.

Just watch out for allergy risks, as some natural ingredients may not suit sensitive pups.

Be sure to also check out the best sulfur shampoo for more options! Also, here is the price history so you know exactly when to buy!

Price history for Arava Dog Shampoo on Amazon

E3 Medicated Dog & Cat Shampoo

E3K9 Medicated Dog & Cat Shampoo - Antifungal & Itchy Skin Relief with Ketoc & Thymol - Hot Spot, Mange, Seborrhea Treatment - Antifungal Dog Shampoo for Yeast
Highlights
Effective skin relief
Good for coat health
Pleasant scent

Its powerful antifungal properties help combat yeast infections and soothe irritated skin, making your pet feel comfortable quickly.

We appreciate how it rejuvenates the coat, leaving it shiny and healthy after each wash.

The pleasant scent makes bath time more enjoyable for both pet and owner, and its long-lasting odor control keeps your furry friend smelling fresh for hours.

However, it’s important to note that it may not provide instant itch relief for all dogs, and might not suit every skin type.

Overall, a strong choice for maintaining your pet’s skin health and coat vitality.

Be sure to also check out the best allergy shampoo for more options! Also, here is the price history so you know exactly when to buy!

Price history for E3 Medicated Dog & Cat Shampoo on Amazon

Davis Sulfur Benz Shampoo

Davis Sulfur Benz Shampoo for Pets, 12 oz
Highlights
Effective for skin issues
Reduces dandruff and dander
helps skin and hair growth

Its powerful combination of 2.5% micronized Benzoyl Peroxide, 2% sulfur, and salicylic acid works effectively to target skin conditions that require a degreasing or keratolytic approach.

It’s especially great for reducing dandruff and dander while encouraging healthy skin and coat growth.

While the fragrance isn’t floral—which might matter to some pet owners—the shampoo's ability to open hair follicles and promote recovery makes it a reliable choice.

Keep in mind, results might require multiple uses, but it’s a solid option for tough skin issues in dogs.

Be sure to also check out the best shampoo cap for more options! Also, here is the price history so you know exactly when to buy!

Price history for Davis Sulfur Benz Shampoo on Amazon

Healthy Paw Life Dog Shampoo Mange Shampoo

Antiparasitic & Antiseborrheic Dog Shampoo (8 fl oz)
Highlights
Fast-acting relief
Gentle & deodorizing
Broad spectrum solution

Healthy Paw Life's medicated shampoo offers fast-acting relief for a variety of skin issues, making your pup feel comfortable sooner rather than later.

Its gentle formulation with oatmeal, lavender, sulfur, and salicylic acid helps soothe irritated skin without harshness, all while leaving behind a pleasant, fresh scent.

The broad spectrum approach tackles seborrhea, mange, and parasitic infections effectively—saving you trips to the vet and money on prescriptions.

However, keep an eye out for irritation in sensitive breeds.

Overall, a cost-effective choice for maintaining your dog's skin health.

Be sure to also check out the best egg shampoo for hair growth for more options! Also, here is the price history so you know exactly when to buy!

Price history for Healthy Paw Life Dog Shampoo on Amazon

Smiling Paws Pets

Smiling Paws Pets Itch Relief Shampoo & Brush for Pets - Contains Benzoyl Peroxide - Kills Fleas - Relieves Allergies, Itching, Dermatitis, Mange, Dandruff, Acne, Demodex, Seborrhea, Pyoderma - 12oz
Highlights
Effective itch relief
Gentle for SENSITIVE SKIN
Trusted by VETERINARIANS

Smiling Paws' medicated shampoo truly delivers effective itch relief without compromising on safety or scent.

Its gentle, sulfate-free formula is a godsend for pets with sensitive skin, soothing irritation and helping keep pores clear.

We love that it’s used by vets and pet lovers alike, giving it extra credibility.

While it may not work for every pet and has limited scent options, consistent use shows promising results.

Plus, knowing it’s made in the USA with eco-friendly ingredients makes it a trustworthy choice for caring owners.

Be sure to also check out the best pantene shampoo for hair growth for more options! Also, here is the price history so you know exactly when to buy!

Price history for Smiling Paws Pets on Amazon

Davis Manufacturing Sulfur Tar Dog Shampoo

Davis Manufacturing Sulfur Tar Shampoo for Pets, 12 oz (Pack of 1), STS12
Highlights
Treats multiple skin issues
Moisturizes skin effectively
Effective for skin conditions

This medicated shampoo targets a range of skin issues, from dandruff to dermatitis and even flea bites, making it a versatile choice for dog owners.

The powerful blend of 2% Sulfur, coal tar, zinc, and salicylic acid works wonders to fight itching, irritation, and flaking while simultaneously moisturizing the skin.

Ideal for all breed sizes and safe for puppies over 8 weeks, it’s a reliable, ready-to-use solution made in the USA.

Just be prepared for the strong medicinal scent — it’s highly effective but might take some getting used to!

Be sure to also check out the best suave shampoo for oily hair for more options! Also, here is the price history so you know exactly when to buy!

Price history for Davis Manufacturing Sulfur Tar Dog Shampoo on Amazon

Davis Miconazole Pet Shampoo Mange Shampoo

Davis Miconazole Pet Shampoo, 12 Oz
Highlights
Effective fungal relief
Moisturizing with oatmeal
Dye and fragrance free

The Miconazole Pet Shampoo delivers quick and soothing relief from fungal infections, making it a go-to for pet owners struggling with itchy, flaky skin.

The 2% colloidal oatmeal works magic by locking in moisture and calming irritated skin, all without any dyes or fragrances that could cause further irritation.

While it does require a bit of patience during the soaking process—especially for smaller animals—its effectiveness justifies the extra time.

Keep in mind, the price is on the higher side, but the benefits for your pet's health and comfort are worth it.

Be sure to also check out the best pantene shampoo for colored hair for more options! Also, here is the price history so you know exactly when to buy!

Price history for Davis Miconazole Pet Shampoo on Amazon

Happy Jack

Happy Jack Xylecide, Itch Relief Shampoo for Dogs, Control Ringworms, Itchy Skin Treatment for Hot Spots, Seborrheic Dermatitis, Dandruff, Psoriasis, Eczema, Kennel Itch (12 oz)
Highlights
Controls ringworms effectively
Soothes chronic skin issues
Fast-acting relief

This HAPPY JACK Mange Shampoo is a true standout when it comes to controlling ringworms and soothing chronic skin issues like dermatitis, eczema, and dandruff.

Its fast-acting formula delivers relief in just a few days, which makes caring for your pup much easier.

The powerful anti-fungal ingredients, like Chloroxylenol, target fungi effectively, helping to prevent the spread to other areas or pets.

While the cap can crack over time and some dogs might need a different approach, overall, this shampoo provides reliable, soothing relief and is a trusted name since 1946.

Be sure to also check out the best detangler shampoo and conditioner for more options! Also, here is the price history so you know exactly when to buy!

Price history for Happy Jack on Amazon

Healthy Paw Life Lime Sulfur Shampoo

Classic's Lime Sulfur Pet Shampoo - Pet Care and Veterinary Solution for Itchy and Dry Skin - Safe for Dog, Cat, Puppy, Kitten, Horse
Highlights
Effective for skin issues
Relieves itching quickly
Gentle with lavender scent

Healthy Paw Life's medicated shampoo is a game-changer for pets struggling with skin irritations.

Its lime sulfur and oatmeal formula work hard to soothe and treat a variety of issues, from mange to bacterial infections.

The lavender scent adds a touch of freshness, making bath times more bearable for both pet and owner.

While the strong sulfur odor might catch some off guard initially, it does fade as your pet’s skin improves.

Overall, for a cost-effective, broad-spectrum solution, this shampoo earns a solid spot in our top picks!

Be sure to also check out the best vanilla shampoo and conditioner for more options! Also, here is the price history so you know exactly when to buy!

Price history for Healthy Paw Life Lime Sulfur Shampoo on Amazon

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